- Non -lactam cell wall inhibitor
| Antibiotic | Indication | Considerations |
|---|---|---|
| Lipopeptides | ||
| Vancomycin & teicoplanin | Complicated Gram +ve including MRSA. Oral for C. diff | Dose IV to trough serum concentration |
| Polymyxins | ||
| Colistin, polymyxin B | Multi-resistance Gram -ve | Nephrotoxicity in ~50%. Inhaled colistin for VAP |