Drug Class | Calcium channel blocker |
---|---|
Mechanism | Interfere with the inward movement of calcium ions into cells * relaxation of vascular smooth muscle * ↓ myocardial contractility * ↓ conduction at AV node, ↑ refractory period * ↓ afterload and HR - ↓ Oxygen consumption |
Typical Dose | 5mg to up 10mg |
Indications | * Angina * HTN |
Contra-indications | * Cardiogenic shock * Significant Aortic Stenosis * Unstable Angina |
Side-effects | **Ankle oedema,**abdominal pain, nausea |
Interactions | * P450 stuff |
Elimination | |
Additional Notes |