Drug ClassCalcium channel blocker
MechanismInterfere with the inward movement of calcium ions into cells * relaxation of vascular smooth muscle * ↓ myocardial contractility * ↓ conduction at AV node, ↑ refractory period * ↓ afterload and HR - ↓ Oxygen consumption
Typical Dose5mg to up 10mg
Indications* Angina * HTN
Contra-indications* Cardiogenic shock * Significant Aortic Stenosis * Unstable Angina
Side-effects**Ankle oedema,**abdominal pain, nausea
Interactions* P450 stuff
Elimination
Additional Notes