| Mechanism | * Inhibits thyroid peroxidise which is necessary for thyroid synthesis |
| Typical Dose | 15-40mg up to 60mg for blocking therapy |
| Indications | Hyperthyroid |
| Contra-indications | Severe blood disorders High caution in Pregnancy - congenital malformations esp in 1st trimester |
| Side-effects | Common: GI disturbance, headache, skin rash, pruritis, joint pain Rare: agranulocytosis, Jaundice, alopecia |
| Interactions | |
| Elimination | |
| Additional Notes | Regular monitoring is essential. Graves treatment should continue for at least a year. |