- Chronic phase
- Accelerated phase
- Blast phase
Slow growing cancer of mature myeloid cells which don’t function properly
- Main findings is abnormal FBC results, splenomegaly, constitutional symptoms & hyperviscosity
- Caused by Philadelphia chromosome t(9;22) long arm - forming BCR-ABL gene
- Good prognosis with imatinib - tyrosine kinase inhibitor 95%
- Unless transforms into Acute myeloid leukaemia