- Malignant clonal proliferation of cells within structures
- Precursor of invasive carcinoma
- Most commonly identified as microcalcification
- Invasive ductal carcinoma is most common breast cancer
Nottingham Prognostic Index
- Used to determine prognosis following surgery for breast cancer
- Calculated using size of tumour; number of involved lymph nodes, and grade of tumour
Molecular markers
- Cancer may express Estrogen Receptor (ER), Progesterone Receptor (PR), HER2 (Human Epidermal growth factor Receptor)
- Caner may change with hormones
- Allows for targeted treatments eg Tamoxifen (ER), Trastuzumab (HER2)