Tricuspid regurgitation

Pan-systolic murmur - split second heart sound due to the pulmonary valve closing earlier than aortic as the right ventricle empties fast than left

Other signs of tricuspid regurgitation:

  • Thrill in the tricuspid area on palpation
  • Raised JVP with giant C-V waves (Lancisi’s sign)
  • Pulsatile liver (due to regurgitation into the venous system)
  • Peripheral oedema
  • Ascites

Causes of tricuspid regurgitation:

  • Pressure due to left-sided heart failure or pulmonary hypertension (“functional”)
  • Infective endocarditis
  • Rheumatic heart disease
  • Carcinoid syndrome
  • Ebstein’s anomaly
  • Connective tissue disorders, such as Marfan syndrome

Pulmonary stenosis

Ejection systolic murmur heard better in deep inspiration Widely split second heart sound for the same reason as above.

Usually congenital - Tetralogy of Fallotand Noonan syndrome

Signs of pulmonary stenosis:

  • Thrill in the pulmonary area on palpation
  • Raised JVP with giant A waves (due to the right atrium contracting against a hypertrophic right ventricle)
  • Peripheral oedema
  • Ascites

Tetralogy of Fallot

  • Ventricular septal defect (VSD)
  • Overriding aorta
  • Pulmonary valve stenosis
  • Right ventricular hypertrophy