Most common heritable bleeding disorder - defect in quality or quantity of vWF. Each type or more severe Type 1 - quantitative defect, autosomal dominant Type 2 - qualitative defect, autosomal dominant Type 3 - no vWF produced
PT normal, aPTT (\uparrow\uparrow) (transport FVIII so intrinsic pathway affected)
Treatment with DDAVP, TXA