- Ampicillin and Amoxicillin should be avoided in patients with pharyngitis when glandular fever is considered a possibility as it may cause a maculopapular rash due to the glandular fever, which may be mistaken for an allergic reaction
- Antibiotic treatment is not routinely indicated for pharyngitis and glandular fever.
- Phenoxymethylpenicillin (penicillin V) may substitute Amoxicillin/ampicillin in cases when antibiotic therapy is desired.