| Mechanism | Inhibits bacterial cell wall synthesis by preventing cross-linking between peptidoglycan chains |
| Typical Dose | 500mg TDS |
| Indications | * Gram +ve bacterial infections (strep, stap) * Gram -ve bacterial infections (H. influenzae) * Helicobacter pylori eradication * Infective Endocarditis prophylaxis prior to dental surgery |
| Contra-indications | Penicillin hypersensitivity |
| Side-effects | Skin rash, diarrhoea, N&V, candida vaginitis |
| Interactions | OCP: decreased effectiveness of OCP |
| Elimination | |
| Additional Notes | Certain strains of bacteria produce β-lactamase - Co-amoxiclav required |