• Development of coagulopathy INR >1.5
  • Encephalopathy
  • May occur suddenly in the previously healthy liver
Hyper Acute<7 day onset
Acute8-21 days
Subacute4-26 weeks

Anything that harms the liver can cause liver failure and associated symptoms - Jaundice, hepatic encephalopathy, asterixis etc

Commonest causes: