| Drug Class | Anti-diarrhoeal agent |
|---|---|
| Mechanism | Acts on opioid receptors in myenteric plexus to inhibit peristalsis (inhibits ACh release) |
| Typical Dose | 2-4mg OD up to 16mg in 2 doses |
| Indications | * Acute & chronic diarrhoea * Faecal incontinence |
| Contra-indications | * Active Ulcerative Colitis * Abx-associated colitis * Dysentery |
| Side-effects | * GI disorders (abdo cramps) * Headache * Nausea |
| Interactions | Desmopressin |
| Elimination | |
| Additional Notes |