Drug ClassAminosalicylates
MechanismRelease 5-aminosalicyclate acid in the bowel
Typical Dose2.4-4.8g OD
Indications* Mild-moderate Ulcerative Colitis/Crohn’s * Maintenance of remission * RA
Contra-indications* Salicylate hypersensitivity * Renal impairment
Side-effects* GI disturbances * Headache * Arthralgia * Leucopenia
InteractionsNo severe
Elimination
Additional NotesRenal impairment should be monitored for 3 months prior to starting treatment, and annually during treatment