Drug Class | Aminosalicylates |
---|---|
Mechanism | Release 5-aminosalicyclate acid in the bowel |
Typical Dose | 2.4-4.8g OD |
Indications | * Mild-moderate Ulcerative Colitis/Crohn’s * Maintenance of remission * RA |
Contra-indications | * Salicylate hypersensitivity * Renal impairment |
Side-effects | * GI disturbances * Headache * Arthralgia * Leucopenia |
Interactions | No severe |
Elimination | |
Additional Notes | Renal impairment should be monitored for 3 months prior to starting treatment, and annually during treatment |