| Drug Class | Anti-convulsant |
|---|---|
| Mechanism | ↑ GABA content of the brain - inhibits GABA re-uptake |
| Typical Dose | 600mg daily in 1-2 divided doses |
| Indications | All forms of Epilepsy |
| Contra-indications | * Hepatic dysfunction * Porphyria |
| Side-effects | Common: N&V, weight gain Rarely: hepatic failure, pancreatitis, blood dyscrasia, sedation, transient hair loss |
| Interactions | Neuroleptics: decreased effects of Na valproate TCA: ↓ anticonvulsant effects of Na valproate |
| Elimination | |
| Additional Notes |