Viruses

Herpes viruses

Virus	Transmission	Clinical	Latency in
HSV-1	Direct contact	Cold sores, encephalitis	Trigeminal ganglia
HSV-2	Direct contact	Genital ulcers, meningitis, neonatal	Sacral ganglia
VZV	Resp droplet	Chicken pox, shingles	whole CNS
EBV	Saliva/genital	Infectious Mononucleosis	B cells
CMV	Saliva/genital	Mononucleosis, congential	Myeloid progenitors

Respiratory viruses

Virus	Transmission	Clinical	Other
Rhinovirus	Resp droplet	Common cold
Influenza	Resp droplet	Primary influenza, post-influenza bacterial pneumonia
RSV	Resp droplet	Bronchiolitis	Commonest in young children

Hepatitis viruses

Hepatitis	Transmission	Clinical	Other
A	Faecal-oral	Acute hepatitis	Poverty, returning travellers, MSM
E	Faecal-oral	Acute hepatitis	Pork consumption
B	Sexual, vertical	Acute & chronic hepatitis, cirrhosis	Risk of chronicity inversley related to age at aquisition
C	Sexual, vertical	Acute & chronic, cirrhosis	IV drug users
D	Sexual, vertical		Requires Hep B for disease

Transmitted via GIT

Virus	Transmission	Clinical	Other
Norovirus	Faecal-oral	Profuse vomitting	Aerosilised vomit aids spread
Rotavirus	Faecal-oral	Diarrhoea and vomitting	Vaccine is routine
Enteroviruses	Faecal-oral	Polio, fever-rash, meningitis, bad in neonates	Commonest cause of viral meningitis

Childhood viruses

Virus	Transmission	Clinical	Other
Mumps	Resp droplet	Parotiditis, orchitis	Mumps meningoencephalitis can = deafness
Measles	Resp droplet	Measles, Encephalitis, SSPE	Rash starts on face + cough
Rubella	Resp droplet	German measles, congenital rubella	Congenital = deafness, bilateral Cataracts, cardiac defects
Parvovirus B19	Resp droplet	Erythema infectiosum (red rash on face), aplastic crisis	Infects erythrocyte progenitors