| Mechanism | GABA-mediated inhibitory transmission in the CNS |
| Typical Dose | 100-200mg |
| Indications | * Generalised tonic-clonic siezures * Partial seizures * Trigeminal neuralgia/chronic neurogenic pain * Biopolar prophylaxis * Adjunct in alcohol withdrawal |
| Contra-indications | * History of Bone marrow Depression * AV node conduction abnormalities * Porphyria |
| Side-effects | Common: drowsiness, ataxia, blurred vision, confusion Rarely: agranulocytosis, thrombocytopenia |
| Interactions | Clarithromycin: carbamazepine metabolism slowed Induce Cytochrome P450 - so anything interacts with that |
| Elimination | |
| Additional Notes | |