| Mechanism | Blocks ACh - inhibit parasympathetic pathway which is responsible for smooth muscle contraction. |
| Typical Dose | 250-500 micrograms 3-4 times a day of neb |
| Indications | * Reversible airway obstruction (particularly COPD) * Severe/life-threatening asthma * Acute bronchospasm |
| Contra-indications | Caution: prostatic hyperplasia, bladder outflow obstructions, patients at risk of glaucoma |
| Side-effects | Arrhythmias, constipation, cough, dizziness, dry mouth, headache, nausea |
| Interactions | * Avoid with clarithromycin/Erythromycin * ↑ risk of side effect antidepressants * ↓ effect of sublingual nitrates (due to dry mouth) |
| Elimination | |
| Additional Notes | |