B or T cell usually solid malignancy in a lymph node

B symptoms

  • Fever
  • Weight loss
  • Night sweats

Hodgkin’s Lymphoma

  • Presence of Reed-Steinberg cells
  • Bimodal age distribution
  • 90% cure rate with radiotherapy/chemo
  • Lymph node pain on drinking alcohol

Non-Hodkin’s lymphoma

  • Everything else - follicular lymphoma most common, t(14;18)
  • Risk factors of HIV, EBV, H. pylori, Hep B&C, pesticides and other carcinogens