Cellulitis is a common bacterial skin infection that affects the deeper layers of the skin and the subcutaneous tissues. It typically occurs when bacteria enter the skin through a break or crack, causing redness, swelling, and pain. Cellulitis can occur anywhere on the body and may spread rapidly if left untreated.

Ludwig’s Angina - cellulitis of the submandibular space (often after dental procedures)

Causes/Factors

Most common bacteria - Strep. pyogenes and Staph. aureus

  • Skin Injuries: Cuts, wounds, insect bites, or surgical incisions.
  • Skin Conditions: Atopic dermatitis (eczema), dermatitis, or other pre-existing skin disorders.
  • Weakened Immune System: Conditions like Diabetes Mellitus or immunodeficiency.
  • Lymphedema: Swelling that impairs the normal flow of lymph.

Symptoms

  • Demarcation: Well-defined borders between affected and unaffected skin.
  • Systemic Symptoms: Fever and generalized malaise.
  • Lymphangitis: Red streaks indicating spread along lymph vessels.

Signs

  • Calor, dolor, rubor, tumor (heat, tenderness, erythema, swelling)
  • Fever and Chills: if septic
  • Skin Lesions: Blistering or oozing of clear fluid.

Diagnostic Tests

Diagnosing Cellulitis is primarily based on clinical evaluation, but additional tests may be used to exclude a Deep Vein Thrombosis:

  • FBC, CRP and possible imaging

Management

  • Elevate affected limb
  • Antibiotics (PO/IV dependant on severity) - commonly Amoxicillin / ben pen + flucloxacillin. If penicillin allergic - Clindamycin and ceftriaxone. 10 day course PO but up to 14 days IV if systemic.

Complications/red Flags

  • Septicaemia
  • Abscess formation
  • Recurrence
  • Chronic skin discolouration