| Mechanism | Irreversible COXI and COXII inhibitor |
| Typical Dose | 75g OD - 300mg loading in MI |
| Indications | * Secondary prevention for CVD * ACS * Ischemic Stroke/TIA * OTC pain relief |
| Contra-indications | * Active bleeding * Peptic ulcer * Haemophilia * Breast feeding * Pregnancy during the third trimester |
| Side-effects | * Bronchospasm * GI haemorrhage |
| Interactions | |
| Elimination | |
| Additional Notes | Do not give to anyone under the age of 16 esp after a viral infection - Reye’s syndrome. Risk of hepatic and cerebral swelling. |