Drug ClassPeptide hormone
MechanismLowers plasma glucose concentration: * Glucose transport into fat and muscle cells * Stimulating glycogen synthesis * Inhibiting gluconeogenesis
Typical Dose(According to requirements)
Indications* Diabetes type I (and 4th line for TII) * Ketoacidosis * Hyperglycaemic hyperosmotic non-ketotic coma * Emergency treatment of Hyperkalaemia
Contra-indicationsCaution in renal impairment
Side-effects* Hypoglycaemia * Weight gain * Oedema
InteractionsB-blockers - mask warning signs of Hypoglycaemia
Elimination
Additional NotesSee Diabetes management for the different types of insulin dose and how to prescribe